I'm having issues with the SD2SNES and Earthbound. Sometimes, the screen will flicker/twitch when scrolling text at random; no other games do this. Current SDSNES firmware is 0.1.7e, all files and folders are set up correctly.
Currently running it on an Analogue Super NT, using firmware 4.4.
It's hard to describe, but essentially, it will randomly flicker/shake similar to how a video signal looks when there's a loose connection. I unplugged and plugged the HDMI cable back in and it still occurs. Oddly enough, testing various games like Earthworm Jim 2, Final Fantasy VI and Chrono Trigger don't exhibit this anomaly, Earthbound seems to be the only game to do it. I don't know if it's the firmware itself, a bad ROM dump, or what, but it is distracting and even painful to my eyes to play with the random flickering. It happens typically only in battle when there's scrolling text and when the battle is finished.
Edit: As soon as I can manage to record a video, I will post it here.